生醫材料及表面分析之檢測原理-學期成績(1-15-2009)

知識管理系統

1.      Shiuh-Bin Fang, Hung-Chang Lee, Jen-Jan Hu, Shao-Yi Hou, Hsuan-Liang Liu, Hsu-Wei Fang*, “Dose-dependent effect of Lactobacillus GG on quantitative reduction of faecal rotavirus shedding in children”, Journal of Tropical Pediatrics (accepted,  Jan. 8, 2009)

2.      Chih-Hung Chang, Siow-Tung Loo, Hsuan-Liang Liu, Hsu-Wei Fang, Hsin-Yi Lin*, “Can low frequency electromagnetic field help cartilage tissue engineering?”, Journal of Biomedical Materials Research: Part A (accepted, Nov. 21, 2008)

3.      Hsu-Wei Fang*, Yu-Chih Su, Huei-Ting Huang, Wei-Bor Tsai, Hsuan-Liang Liu, “Investigation of the friction induced conformational change of protein and wear of UHMWPE by a wear process with microfabricated surfaces”, Materials Science and Engineering: C (accepted, Sep. 22, 2008)

4.      Jung-Yen Yang, Yen-Chung Ting, Juin-Yih Lai, Hsuan-Liang Liu, Hsu-Wei Fang, Wei-Bor Tsai*, “Quantitative analysis of osteoblast-like cells (MG63) morphology on nanogrooved substrata with various groove and ridge dimensions”, Journal of Biomedical Materials Research: Part A, (accepted, Jan. 14, 2008)

5.      Hsu-Wei Fang*, Man-Ching Hsieh, Cheng-Yen Tsai, Huei-Ting Huang, “Conformational and adsorptive characteristics of albumin affect interfacial protein boundary lubrication: from experimental to molecular dynamics simulation approaches”, Colloids and Surfaces B: Biointerfaces 68, pp. 171-177, 2009. (Feb. 2009)

6.      Peng-Yuan Wang, Hsiang-Hong Chow, Hsu-Wei Fang, Wei-Bor Tsai*,” Modulation of Gene Expression of Rabbit Chondrocytes by Dynamic Compression in Polyurethane Scaffolds with Collagen Gel Encapsulation”, Journal of Biomaterials Applications 23, pp. 347-366, 2009. (Jan. 2009)

7.      Jian-Hua Zhao, Hsuan-Liang Liu*, Yi-Fan Liu, Hsin-Yi Lin, Hsu-Wei Fang, Yih Ho, Wei-Bor Tsai, “Molecular Dynamics Simulations to Investigate the Aggregation Behaviors of the Ab(17-42) Oligomers”, Journal of Biomolecular Structure & Dynamics 26(4), pp. 481-490, 2009. (Feb. 2009)

8.      Hsuan-Liang Liu*, Jung-Tang Huang, Po-Sheng Fang, Yi-Fan Liu, Ming-Kwang Hsu, Chiao-Ling Hsu, Jian-Sheng Liao, Wen-Hui Hsieh, Shao-Yi Hou, Hsin-Yi Lin, Hsu-Wei Fang, Recent Patents for nucleic acid sequencing and its applications”, Current Topics in Biotechnology 4, pp. 21-33, 2008.

9.      Sheng-Tung Huang, Chia-Shin Ho, Chun-Mao Lin, Hsu-Wei Fang, Yi-Xiang Peng, “Development and biological evaluation of C60 fulleropyrrolidine- thalidomide dyad as a new anti-inflammation agent”, Bioorganic & Medicinal Chemistry 16 (18), pp. 8619-8626, 2008. (Sep. 2008)

10.  Chien-Ho Chen, Der-Zen Liu, Hsu-Wei Fang, Hong-Jen Liang, Tzu-Sheng Yang, Shyr-Yi Lin*, “Evaluation of multi-target and single-target liposomal drugs for the treatment of gastric cancer”, Bioscience Biotechnology and Biochemistry, 72(6), pp. 1586-1594, 2008. (June 2008)

11.  Chih-Hung Chang, Hsin-Yi Lin, Hsu-Wei Fang, Shiao-Tung Loo, Shi-Je Hung, Chien-Cheng Lin, Cheng-Hung Chou, Feng-Huei Lin*, Hwa-Chang Liu*, “Chondrogenesis From Immortalized Human Mesenchymal Stem Cells: Comparison Between Collagen Gel and Pellet Culture Methods”, Artificial Organs, 32(7), pp. 561-566, 2008. (July 2008)

12.  Hsu-Wei Fang*, Kuo-Yen Li, Tai-Lun Su, Po-Liang Lin, Ji-Sheng Chang, Wen-Chung Chang, “Dip coating assisted polylactic acid deposition on steel surface: film thickness affected by drag force and gravity”, Materials Letters, 62(21-22), pp. 3739-3741, 2008. (Aug 2008)

13.  Jian-Hua Zhao, Ching-Tao Yang, Josephine W. Wu, Wei-Bor Tsai, Hsin-Yi Lin, Hsu-Wei Fang, Yih-Ho, Hsuan-Liang Liu*, “RING domains functioning as E3 ligases reveal distinct structural features: a molecular dynamics simulation study”, Journal of Biomolecular Structure & Dynamics, 26(1), pp. 65-74, 2008. (Aug 2008)

14.  Syang-Peng Rwei*, Saint-Wei Chen, Ching-Feng Mao, Hsu-Wei Fang, “Viscoelasticity and Wearability of Hyaluronate Solutions”, Biochemical Engineering Journal, 40(2), pp. 211-217, 2008. (Jun 1 2008)

15.  Hsu-Wei Fang*, Hsien-Chieh Wang, Teh-Hua Tsai, Wei-Bor Tsai, Shao-Yi Hou, Hsuan-Liang Liu, Wun-Hsin Lee, Yung-Chang Lu, Chun-Hsiung Huang, “Accelerated wear testing with a microfabricated surface to evaluate the lubrication ability of biomolecules on polyethylene”, Journal of Applied Polymer Science , 108(4), pp. 2428-2437, 2008. (May 15, 2008)

16.  Chih-Hung Chang, Hsu-Wei Fang*, Yi-Ching Ho, Huei-Ting Huang, Chondrocyte acting as phagocyte to internalize polyethylene wear particles and leads to the elevations of osteoarthritis associated NO and PGE2”, Biochemical and Biophysical Research Communications, 369(3), pp. 884-888, 2008. (May 9 2008)

17.  Hsuan-Liang Liu*, Fu-Chiang Yang, Chi-Hung Huang, Hsu-Wei Fang, Yung-Chu Cheng, “Artificial neural network to predict the growth of the indigenous Acidthiobacillus thiooxidans”, Chemical Engineering Journal, 137(2), pp. 231-237, 2008. (Apr 1 2008)

18.  Yi-Ching Ho, Shao-Yi Hou, Tzan Fang, Hsuan-Liang Liu, Hsu-Wei Fang*, “Effect of electrostatic field on proliferation and cytokine secretion of macrophage cells”, Biomedical Engineering- Applications, Basis and Communications, 20(1), pp. 47-52, 2008 (Feb, 2008)(EI)

19.  Sheng-Tung Huang*, Jian-Sheng Liao, Hsu-Wei Fang, Chun-Mao Lin, “Synthesis and anti-inflammation evaluation of new C60 fulleropyrrolidines bearing biologically active xanthine”, Bioorganic & Medicinal Chemistry Letters, 18(1), pp. 99-103, 2008. (Jan 1 2008)

20.  Jian-Hua Zhao, Hsuan-Liang Liu*, Hsin-Yi Lin, Chi-Hung Huang, Hsu-Wei Fang, Yih Ho, Wei-Bor Tsai, Wen-Yih Chen, “Chemical chaperone and inhibitor discovery: potential treatments for protein conformational diseases”, Perspectives in Medicinal Chemistry, 1, pp. 39-48, 2007. (Dec 11 2007)

21.  Hsuan-Liang Liu*, Yuan-Min Lin, Jian-Hua Zhao, Man-Ching Hsieh, Hsin-Yi Lin, Chi-Hung Huang, Hsu-Wei Fang, Yih Ho, and Wen-Yih Chen, “Molecular Dynamics Simulations of Human Cystatin C and Its L68Q Varient to Investigate the Domain Swapping Mechanism”, Journal of Biomolecular Structure & Dynamics, 25(2), pp. 135-144, 2007. (Oct 2007)

22.  Hsuan-Liang Liu*, Ching-Tao Yang, Jian-Hua Zhao, Chi-Hung Huang, Hsin-Yi Lin, Hsu-Wei Fang, Yih Ho, Wei-Bor Tsai, “Molecular Dynamics Simulations to Investigate the Effects of Zinc Ions on the Structural Stability of the c-Cbl RING Domain”, Biotechnology Progress, 23(5), pp. 1231-1238, 2007. (Sep-Oct 2007)

23.  Jian-Hua Zhao, Hsuan-Liang Liu*, Hsin-Yi Lin, Chih-Hung Huang, Hsu-Wei Fang, Shau-Wei Tsai, “Semiempirical molecular orbital studies of the acylation step in the lipase-catalyzed ester hydrolysis”, Journal of the Chinese Chemical Society, 54(4), pp. 835-842, 2007. (Aug 2007)

24.  Hsu-Wei Fang*, Meng-Lin Shih, Jian-Hua Zhao, Huei-Ting Huang, Hsin-Yi Lin, Hsuan-Liang Liu, Chih-Hung Chang, Charng-Bin Yang, Hwa-Chang Liu, “Association of polyethylene friction and thermal unfolding of interfacial albumin molecules”, Applied Surface Science, 253(16), pp. 6896-6904, 2007. (Jun 15 2007)

25.  Chih-Hung Chang, Hsu-Wei Fang*, Wei-Ming Lee, Huei-Ting Huang, Man-Ching Hsieh, Chiang-San Chen, “Tribological process induced conformational transformation of protein may change the friction of cartilage”, Materials Letters, 61(16), pp. 3381-3384, 2007. (Jun 2007)

26.  Po-Liang Lin, Hsu-Wei Fang*, Tiffany Tseng, Wun-Hsing Lee, “Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials”, Materials Letters, 61(14-15), pp. 3009-3013, 2007. (Jun 2007)

27.  Hsuan-Liang Liu*, Fu-Chiang Yang, Chi-Hung Huang, Hsu-Wei Fang, Yung-Chu Cheng, “Sensitivity analysis of the semiempirical model for the growth of the indigenous Acidithiobacillus thiooxidans”, Chemical Engineering Journal, 129(1-3), pp. 105-112, 2007. (May 1 2007)

28.  Yuan-Min Lin, Hsuan-Liang Liu*, Jian-Hua Zhao, Chi-Hung Huang, Hsu-Wei Fang, Yih Ho, “Molecular Dynamics Simulations to Investigate the Domain Swapping Mechanism of Human Cystatin C”, Biotechnology Progress 23(3), pp. 577-584, 2007. (May-Jun 2007)

29.  Hsuan-Liang Liu*, Yi-Ching Wu, Jian-Hua Zhao, Yi-Fan Liu, Hsu-Wei Fang, Yih Ho, “Insights into the conformational changes of several human lysozyme variants associated with hereditary systemic amyloidosis”, Biotechnology Progress, 23(1), pp. 246-254, 2007. (Jan-Feb 2007)

30.  Hsu-Wei Fang*, “Characteristic modeling of the wear particle formation process from a tribological testing of polyethylene with controlled surface asperities”, Journal of Applied Polymer Science, 103(1), pp. 587-594, 2007. (Jan 5 2007)

31.  Hsuan-Liang Liu*, Yi-Ching Wu, Jian-Hua Zhao, Hsu-Wei Fang, and Yih Ho, “Structural analysis of human lysozyme using molecular dynamics simulations”, Journal of Biomolecular Structure and Dynamics, 24(3), pp. 229-238, 2006. (Dec 2006)

32.  Hsu-Wei Fang*, Charng-Bin Yang, Chih-Hung Chang, Chun-Hsiung Huang, Hsuan-Liang Liu, Shiuh-Bin Fang, The potential role of phagocytic capacity in osteolytic process induced by polyethylene wear particles”, Journal of International Medical Research, 34(6), pp. 655-664, 2006. (Nov-Dec 2006)

33.  Hsu-Wei Fang*, Yi-Ching Ho, Charng-Bin Yang, Hsuan-Liang Liu, Fang-Yuan Ho, Yung-Chang Lu, Hon-Ming Ma, Chun-Hsiung Huang, “Preparation of UHMWPE particles and establishment of inverted macrophage cell model to investigate wear particles induced bioactivities”, Journal of Biochemical and Biophysical Methods, 68(3), pp. 175-187, 2006. (Oct 31 2006)

34.  Charng-Bin Yang, Hsu-Wei Fang*, Hsuan-Liang Liu, Chih-Hung Chang, Man-Ching Hsieh, Wei-Ming Lee, Huei-Ting Huang, “Frictional characteristics of the tribological unfolding albumin for polyethylene and cartilage”, Chemical Physics Letters, 431(4-6), pp. 380-384, 2006. (Nov 24 2006)

35.  張至宏, 黃彗婷, 方旭偉, 林峰輝, 郭宗甫, 劉華昌*, “軟骨組織工程之回顧與展望”, 中華創傷骨科雜誌, Vol. 8, No. 10, pp. 970-973, 2006.

36.  Chih-Hung Chang, Hsu-Wei Fang*, Hwa-Chang Liu, Feng-Huei Lin, Wei-Ming Lee, Huei-Ting Huang, Wun-Hsing Lee, Chiang-San Chen, “Effects of tribochemistry of synovial fluids on the performance of unicondylar knee arthroplasty: development of the testing model”, Journal of Orthopaedic Surgery, Taiwan, 23, no.1, pp. 10-15, 2006.

37.  Hsu-Wei Fang*, Charng-Bin Yang, Yu-Chih Su, Yi-Ching Ho, Cheng-Yen Tsai, Chun-Hsiung Huang, “Generation of wear particles with specific size and shape for pre-clinical tests of orthopaedic implants”, Journal of Orthopaedic Surgery, Taiwan, 23, no.1, pp. 1-9, 2006.

38.  Hsu-Wei Fang*, Stephen M. Hsu, Jan V. Sengers, “Single wedge sliding tests to investigate the mechanism of UHMWPE particle generation with microfabricated surface textures”, Polymer Testing, 25(3), pp. 424-434, 2006. (May 2006)

39.  Hsu-Wei Fang*, Yu-Chih. Su, Chun-Hsiung Huang, Charng-Bin Yang, “Influence of biological lubricant on the morphology of UHMWPE wear particles generated with microfabricated surface textures”, Materials Chemistry and Physics, 95(2-3), pp. 280-288, 2006. (Feb 10 2006)

40.  Weiping Ren, Shangyoung Yang, Hsu-Wei Fang, Stephen M. Hsu, and Paul H. Wooley, “Distinct gene expression of receptor activator of nuclear factor-kB andrank ligandin the inflammatory response to variant”, Biomaterials, 24(26), pp. 4819-4826, 2003. (Nov 2003)

41.  Hsu-Wei Fang, Stephen M. Hsu*, Jan V. Sengers, “Generation of narrowly distributed ultra-high molecular weight polyethylene particles by surface texturing techniques”, Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 67B(2), pp. 741-749, 2003. (Nov 12 2003)

42.  Hsu-Wei Fang, Stephen M. Hsu*, Jan V. Sengers, “Surface texture design to generate specific sizes and shapes of UHMWPE wear particles”, Materialwissenschaft und Werkstofftechnik (Materials Science and Engineering Technology), 34(10-11), pp. 976-988, 2003. (Oct-Nov 2003)

43.  Hwa-Chang Liu*, Ruei-Ming Chen, Feng-Huei Lin, Hsu-Wei Fang, “Sintered b-dicalcium phosphate particles induce intracellular reactive oxygen species in rat osteoblasts”, Biomedical Engineering Applications, Basis Communications, v11, n5, pp. 259-264, 1999.

44.  Wei-Ming Lu*, Chih-Ming Lan, Hsu-Wei Fang, “Local heat transfer in a stirred vessel with and without Aeration”, Journal of Chemical Engineering of Japan, v28, n6, pp. 666-672, 1995.

書籍

1.          Hsu-Wei Fang, Stephen M. Hsu, Jan V. Sengers, “Ultra-High Molecular Weight Polyethylene Wear Particle Effects on Bioactivity”, National Institute of Standards and Technology Special Publication 1002, 2003.

2.          Hsu-Wei Fang, “Ultra-High Molecular Weight Polyethylene Wear Particle Effects on Bioactivity”, Ph.D. Dissertation, University of Maryland at College Park, 2003.

3.          Hsu-Wei Fang, “Stirling Engine Performace Modeling”, M.S. Thesis, University of Maryland at College Park, 1996.

發明專利

1.          Hsu-Wei Fang*, “Method for generating polymeric wear particles”, US Patent (submitted, April 2006, Patent application # 20070281032)

2.          Hsu-Wei Fang*, Yi-Ching Ho, “A method and device for testing cell responses to polymer particles in vitro”, US Patent (submitted, March 2006, Patent application # 20070281290)

3.          方旭偉*、蘇毓智,高分子微粒之切割裝置與方法 中華民國發明專利 I 301443

4.  方旭偉*、何宜靜, 體外檢測高分子顆粒對細胞影響的方法與裝置, 中華民國專利 (發明專利申請中) (申請日期2005/12/27,申請案號94146811, 公開日期 2007/7/1, 公開編號 200724892)