Welcome to the

Biomolecular Simulation Lab.Dr. Hsuan-Liang Liu, Professor

 

研究領域 Research fields

 

 

Ski in Japan

 

Ph: +886-2-27712171 ext. 2542

Fax: +886-2-27317117

e-mail: f10894@ntut.edu.tw

Address: No. 1 Sec. 3 ZhongXiao E. Rd., Taipei, TAIWAN 10608

基本資料

 

Education

School

Major

Degree

Time

Iowa State University

Chemical Engineering

Ph.D.

1993/08 ~ 1998/05

National Taiwan University

Chemical Engineering

B.S.

1987/10 ~ 1991/06

 

基本資料

 

Current Occupation & Experiences

Institute

Department

Position

Duration

National Taipei University of Technology

Institute of Biotechnology

Head

2005/02~now

National Taipei University of Technology

Department of Chemical Engineering

Institute of Biotechnology

Professor

2006/02 ~ now

National Taipei University of Technology

Department of Chemical Engineering

Institute of Biotechnology

Associate professor

2003/02 ~ 2006/01

National Taipei University of Technology

Department of Chemical Engineering

Assistant professor

1999/02 ~ 2003/01

TNC Industrial Co., Ltd.

 

Consultant

1999/03 ~ 2000/02

Chung Hua Institution for Economic Research

Power center

Project consultant

1999/10 ~ 2000/09

TNC Industrial Co., Ltd.

CEO office

Specialist

1998/07 ~ 1999/02

Iowa State University

Department of Chemical Engineering

Research assistant

1993/08 ~ 1998/05

Taiwan army

 

Second lieutenant

1991/07 ~ 1993/05

 

基本資料

 

 Research fields

Research fields

1.Structural Biology

2.Biomolecular Simulations

3.Genetic & Protein Engineering

4.Environmental Biology

 

基本資料

 

 Publications

   Journal papers (*Corresponding author)

                                 (1st = first author; corres = corresponding author)

Status
Authorship
SCI
EI
Review
Total
Published
1st
3
-
-
3
1st and corres
43
1
1
45
Not 1st
13
-
-
13
corres
10
-
2
12
Subtotal
69
1
3
73
Accepted or in press
1st and corres
-
-
-
0

corres

-

-

1

1

Not 1st
2
1
-
3
Subtotal
2
1
1
4
In revision
1st and corres
1
-
-
1
Not 1st
-
-
-
0
corres
1
-
-
1
Subtotal
2
0
0
2
Submitted
1st and corres
-
-
-
0
Not 1st 2 - - 2
corres
1
-
-
1
Subtotal
3
0
0
3
Total
75
2
4
82

1998

1.
Hsuan-Liang Liu, Pedro M. Coutinho, Clark Ford and Peter J. Reilly*, “Mutations to alter Aspergillus awamori glucoamylase selectivity. III. 
Asn20®Cys/Ala27®Cys, Ala27®Pro, Ser30®Pro, Lys108®Arg, Lys108®Met Gly137®Ala, 311-314 Loop, Tyr312®Trp and Ser436®Pro”, 
Protein Engineering, 11(5), 389-398 (Nov., 1998) (SCI, impact factor: 3.209) [abstract] [full text (PDF)]
1999
2.
Hsuan-Liang Liu, Clark Ford and Peter J. Reilly*, “Mutations to alter Aspergillus awamori glucoamylase selectivity. IV. Combinations of 
Asn20®Cys/Ala27®Cys, Ser30®Pro, Gly137®Ala, 311-314 Loop, Ser411® Ala and Ser436®Pro”, Protein Engineering, 12 (2), 163-172 
(Feb., 1999) (SCI, impact factor: 3.209) [abstract] [full text (PDF)]
2000
3.
Hsuan-Liang Liu, Clark Ford and Peter J. Reilly*, “Replacement and deletion mutations in the catalytic domain and belt region of Aspergillus awamori 
glucoamylase to enhance thermostability”, Protein Engineering, 13 (9), 655-659 (Sep., 2000) (SCI, impact factor: 3.209) [abstract] [full text (PDF)]
2001
4.
Hsuan-Liang Liu*, “Structural/functional relationships and protein engineering of glucoamylase”, Recent Research and Development in Protein Engineering, 
1, 75-106 (2001) (NSC-89-2311-B-027-001) (Invited review paper)
2002
5.
Hsuan-Liang Liu* and Wen-Chi Wang, “The predicted unfolding order of the b-strands in the starch binding domain from Aspergillus niger glucoamylase”, 
Chemical Physics Letters, 366 (3-4), 284-290 (Nov. 12, 2002) (NSC-89-2311-B-027-001) (SCI, impact factor: 2.526) [abstract] [full text (PDF)]
2003
6.
Hsuan-Liang Liu* and Wen-Chi Wang, “Protein engineering to improve the thermostability of glucoamylase from Aspergillus awamori based on molecular 
dynamics simulations”, Protein Engineering, 16 (1), 19-25 (Jan. 2003) (NSC-89-2311-B-027-001) (SCI, impact factor: 3.209) [abstract] [full text (PDF)]
7.
Hsuan-Liang Liu*, Wen-Chi Wang and Chia-Ming Hsu, “Molecular Dynamics Simulations of the Unfolding Mechanism of the Catalytic Domain from 
Aspergillus awamori var. X100 Glucoamylase”, Journal of Biomolecular Structure and Dynamics, 20 (4), 567-574 (Feb. 2003)
(NSC-89-2214-E-027-006) (SCI, impact factor: 1.407) [abstract] [full text (PDF)]
8.
Hsuan-Liang Liu*, Wen-Jang Chen and Shih-Nung Chou, “Mechanisms of aggregation of alpha- and beta-amylases in aqueous dispersions”, 
Colloids and Surfaces B: Biointerfaces, 28 (2-3), 215-225 (March 10, 2003) (NSC 89-2311-B-027-001) (SCI, impact factor: 1.586) 
[abstract] [full text (PDF)]
9.
Hsuan-Liang Liu*, Yun-Wen Chen and Yang-Chu Cheng, “Toxic Effects of Cadmium and Acetic Acid on the Indigenous Thiobacillus thiooxidans”, 
Journal of the Chinese Institute of Chemical Engineers, 34 (2), 171-176 (March 2003) (NSC-89-2214-E-027-006 & NSC-90-2214-E-027-006) 
(SCI, impact factor: 0.333)[abstract] [full text (PDF)]
10.
Hsuan-Liang Liu*, Yih Ho and Chia-Ming Hsu, “The influence of metal ions on the substrate binding pocket of the human alcohol dehydrogenase b2b2 
by molecular modeling”, Chemical Physics Letters, 372 (1-2), 249-254 (April 2003) (NSC-89-2311-B-027-001) (SCI, impact factor: 2.526) 
[abstract] [full text (PDF)]
11.
Hsuan-Liang Liu* and Wen-Chi Wang, “Molecular dynamics simulations of the unfolding of the starch binding domain from Aspergillus niger 
glucoamylase”, Journal of Biomolecular Structure and Dynamics, 20 (5), 615-622 (April, 2003) (NSC-89-2214-E-027-006) 
(SCI, impact factor: 1.407)[abstract] [full text (PDF)]
12.
Hsuan-Liang Liu*, Yih Ho and Chia-Ming Hsu, “The Effect of Metal Ions on the Binding of Ethanol to Human Alcohol Dehydrogenase b2b2”,
Journal of Biomedical Science, 10 (3), 302-312 (May, 2003) (SCI, impact factor: 2.322) (NSC-89-2311-B-027-001) [abstract] [full text (PDF)]
13.
Hsuan-Liang Liu*, Yann-Chi Shu and Yann-Huei Wu, “Molecular dynamics simulations to determine the optimal loop length in the helix-loop-helix motif”, 
Journal of Biomolecular Structure and Dynamics, 20 (6), 741-746 (June, 2003) (NSC-89-2214-E-027-006) (SCI; impact factor: 1.407) 
[abstract] [full text (PDF)]
14.
Hsiu-Mei Chen*, Cheng-Wei Ho, Jui-Wen Liu, Kun-Ying Lin, Yi-Tung Wang, Chi-Hung Lu and Hsuan-Liang Liu, “Production, IMAC purification, 
and molecular modeling of N-carbamoyl-D-amino acid amidohydrolase C-terminally fused with a six-His peptide”, Biotechnology Progress, 19 (3), 864-873 
(June 6, 2003) (SCI, impact factor: 1.821) [abstract] [full text (PDF)]
15.
Hsuan-Liang Liu* and Chia-Ming Hsu, “The effects of solvent and temperature on the structural integrity of monomeric melittin by molecular dynamics 
simulations”, Chemical Physics Letters, 375 (1-2), 119-125 (June 25, 2003) (NSC-89-2311-B-027-001) (SCI; impact factor: 2.526) 
[abstract] [full text (PDF)]
16.
Hsuan-Liang Liu*, Yih Ho and Chia-Ming Hsu, “Molecular modeling of the chelating of various metal ions to the His-tag motif: A preliminary study”, 
Journal of Biomolecular Structure and Dynamics, 21 (1), 31-42 (August, 2003) (NSC-92-2622-E-027-003-CC3) (SCI, impact factor: 1.407) 
[abstract] [full text (PDF)]
17.
Husan-Liang Liu*, “Waste Minimization at a Nitrocellulose Manufacturing Facility”, International Journal of Environmental Studies A, 60 (4), 353-361 
(August, 2003) (NSC 89-2311-B-027-001) (EI) [abstract] [full text (PDF)]
18.
Hsuan-Liang Liu* and Yuan-Ming Lin, “Stability and Unfolding Mechanism of the N-terminal b-Hairpin from [2Fe-2S] Ferredoxin I by Molecular 
Dynamics Simulations: Solvent Effects”, Journal of the Chinese Chemistry Society, 50 (4), 799-808 (August, 2003) (NSC-89-2214-E-027-006) 
(SCI, impact factor: 0.534) [abstract] [full text (PDF)]
19.
Hsuan-Liang Liu*, Chi-Wei Chiu and Yang-Chu Cheng, “The effect of metabolites from the indigenous Thiobacillus thiooxidans and temperature on 
the bioleaching of cadmium from soil”, Biotechnology and Bioengineering, 83 (6), 638-645 (Sep. 20, 2003) (NSC 89-2214-E-027-006 and 
NSC 90-2214-E-027-006) (SCI, impact factor: 2.173) [abstract] [full text (PDF)]
20.
Hsuan-Liang Liu*, Bor-Yann Chen, Yann-Wen Lan and Yang-Chu Cheng, “SEM and AFM images of pyrite surfaces after bioleaching by the indigenous 
Thiobacillus thiooxidans”, Applied Microbiology and Biotechnology, 62 (4), 414-420 (Sep., 2003) (NSC 89-2214-E-027-006 and 
NSC 90-2214-E-027-006) (SCI; impact factor: 2.034) [abstract] [full text (PDF)]
21.
Hsuan-Liang Liu* and Wen-Chi Wang, “Predicted Unfolding Order of the 13 a-Helices in the Catalytic Domain of Glucoamylase from Aspergillus 
awamori var. X100 by Molecular Dynamics Simulations”, Biotechnology Progress, 19 (5), 1583-1590 (Oct., 2003) (NSC-89-2214-E-027-006)
(SCI, impact factor: 1.821) [abstract] [full text (PDF)]
22.
Hsuan-Liang Liu* and Jin-Chung Lin, “Structural model of the voltage-gated potassium channel Kv1.1 and molecular docking of Tc1 toxin from 
Tityus cambridgei to KcsA and Kv1.1”, Chemical Physics Letters, 381 (5-6), 592-597 (Nov. 18, 2003) (NSC-92-2214-E-027-009) 
(SCI; impact factor: 2.526) [abstract] [full text (PDF)]
23.
Hsuan-Liang Liu*, Determination of the optimum length and type of O-glycosylation in the linker domain of glucoamylase from Aspergillus awamori 
by molecular dynamics simulations”, Journal of the Chinese Institute of Chemical Engineers, 34 (6), 655-660 (Nov., 2003) (NSC-89-2311-B-027-001)
(SCI, impact factor: 0.333)[abstract] [full text (PDF)]
24.
Hsuan-Liang Liu* and Thomas, C.-K. Yang, “Photocatalytic inactivation of Escherichia coli and Lactobacillus helveticus by ZnO and TiO2 activated 
with ultraviolet light”, Process Biochemistry, 39 (4), 475-481 (Dec. 31, 2003) (NSC-89-2214-E-027-006) (SCI; impact factor: 1.796)
[abstract] [full text (PDF)]
25.
Hsuan-Liang Liu* and Chia-Ming Hsu, “The Effects of Various Alcohols on the Stability of Melittin: A Molecular Dynamics Study”, 
Journal of the Chinese Chemical Society, 50 (6), 1235-1240 (Dec., 2003) (NSC-89-2214-E-027-006) (SCI; impact factor: 0.534) 
[abstract] [full text (PDF)]
 
2004
26.
Hsuan-Liang Liu*, Bor-Yann Chen, Yann-Wen Lan and Yang-Chu Cheng, “Biosorption of Zn(II) and Cu(II) by the indigenous Thobacillus 
thiooxidans”, Chemical Engineering Journal, 97 (2-3), 195-201 (Feb. 15, 2004) (NSC 89-2214-E-027-006 and NSC 90-2214-E-027-006) 
(SCI, impact factor: 2.034) [abstract] [full text (PDF)]
27.
Bor-Yann Chen*, Hsuan-Liang Liu, Yuen-Wen Chen and Yang-Chu Cheng, “Dose-Response assessment of Metal Toxicity upon indigenous Thiobacillus 
thiooxidans BC1”, Process Biochemistry, 39 (6), 735-745 (Feb. 25, 2004) (SCI, impact factor: 1.796) [abstract] [full text (PDF)]
28.
Hsuan-Liang Liu*, Bor-Yann Chen, Yann-Wen Lan and Yang-Chu Cheng, “Improved cultivation of the indigenous Acidithibacillus  thiooxidans BC1 
by a fed-batch process”, Journal of the Chinese Institute of Chemical Engineers, 35 (2), 195-201, (March, 2004) (NSC-92-2622-E-027-003-CC3) 
(SCI, impact factor: 0.333) [full text (PDF)]
29.
Hsuan-Liang Liu* and Jin-Chung Lin, “Molecular docking of the scorpion toxin Tc1 to the structural model of the voltage-gated potassium channel Kv1.1
from human Homo sapiens, Journal of Biomolecular Structure and Dynamics, 21 (5), 639-650 (April, 2004) (NSC-92-2214-E-027-009) 
(SCI, impact factor: 1.407) [abstract] [full text (PDF)]
30.

 

Hsuan-Liang Liu*, Chun-Hsiung Teng and Yang-Chu Cheng,, “A semiempirical model for bacterial growth and bioleaching of Acidithiobacillus spp.”, 
Chemical Engineering Journal, 99 (1), 77-87 (May 15, 2004) (NSC 90-2214-E-027-006 and NSC-92-2622-E-027-003-CC3) 
(SCI, impact factor: 2.034) [abstract] [full text (PDF)]
31.
Hsuan-Liang Liu* and Jin-Chung Lin, “A set of homology models of the pore loop domain of six eukaryotic voltage-gated potassium channels 
Kv1.1-Kv1.6”, Proteins: Structure, Function, and Bioinformatics, 55 (3), 558-567(May 15, 2004) (NSC-92-2214-E-027-006) 
(SCI; impact factor: 4.313) [abstract] [full text (PDF)]
32.
Hsuan-Liang Liu*, Wei-Chan Hsieh and Hwai-Shen Liu, “Molecular dynamics simulations to determine the effect of supercritical carbon dioxide on the 
structural integrity of hen egg white lysozyme”, Biotechnology Progress, 20 (3),930-938 (June 4, 2004) (NSC-92-2622-E-027-003-CC3) 
(SCI, impact factor: 1.821) [abstract] [full text (PDF)]
34.
Hsuan-Liang Liu*, Jin-Chung Lin, Wei-Chan Hsieh, Chin-Wen Chen and Yuan-Chen Su, “Molecular dynamics simulations to investigate the temperature 
effect on the main proteinases from various coronaviruses”, Journal of Biomolecular Structure and Dynamics, 22 (1), 65-77 (August 2004) 
(NSC-92-2214-E-027-009) (SCI, impact factor: 1.407) (Fig. 8 appears as cover photo of this issue) [abstract] [full text (PDF)]
35.
Hsuan-Liang Liu*, Yann-Wen Lan and Yang-Chu Cheng, “Optimal production of sulfuric acid by the indigenous Thiobacillus thiooxidans using response 
surface methodology”, Process Biochemistry, 39 (12), 1953-1961 (August 31, 2004) (NSC 89-2214-E-027-006 and NSC 90-2214-E-027-006) 
(SCI, impact factor: 1.796) [abstract] [full text (PDF)]
36.
Bor-Yann Chen*, Shao-Yi Hou, Hsuan-Liang Liu, Don-Jun Wu, Ming-Shu Lin and Yang-Chu Cheng, “Ecologically feasible selection strategy upon 
indigenous Thiobacillus thiooxidans”,Journal of the Chinese Institute of Chemical Engineers, 35 (5), 587-593 (Sep. 2004) 
(NSC 91-2214-E-197-001 and NSC 93-2214-E-197-002) (SCI, impact factor: 0.333) [full text (PDF)]
37.
Hsuan-Liang Liu*, Chiao-Kai Hwang, and Jin-Chung Lin, The stabilizing effects of O-glycosylation on the secondary structural integrity of the designed 
a-loop-a motif by molecular dynamics simulations”,  Journal of Biomolecular Structure and Dynamics, 22 (2), 131-136 (October 2004)
(NSC-93-2622-E-027-005-CC3) (SCI, impact factor: 1.407) [abstract] [full text (PDF)]
38.
Hsuan-Liang Liu*, Jin-Chung Lin, Yih Ho, Wei-Chan Hsieh, Chin-Wen Chen and Yuan-Chen Su, “Structural models and molecular dynamics simulations of 
main proteinase from coronavirus associated with severe acute respiratory syndrome (SARS)”, Journal of the Chinese Chemical Society, 51 (5A), 889-900
(October 2004) (NSC-92-2214-E-027-009)(SCI, impact factor: 0.534) [abstract] [full text (PDF)]
2005
39.
Hsuan-Liang Liu*, Jin-Chung Lin, Yih Ho, and Chin-Wen Chen, “Homology models of main proteinase from coronavirus associated with SARS”, 
Chemical Physics Letters, 401 (1-3), 24-29 (Jan. 1, 2005) (NSC-93-2214-E-027-001) (SCI, impact factor: 2.526) [abstract] [full text (PDF)]
40.
Hsuan-Liang Liu*, Chin-Wen Chen and Jin-Chung Lin, “Homology models of the tetramerization domain of six eukaryotic voltage-gated potassium channels 
Kv1.1-Kv1.6”, Journal of Biomolecular Structure and Dynamics, 22 (4), 387-398 (Feb., 2005) (NSC-93-2214-E-027-001) 
(SCI, impact factor: 1.407) [abstract] [full text (PDF)]
41.
Hsuan-Liang Liu* and Wei-Chan Hsieh, “Molecular dynamics simulations to investigate the thermal unfolding behaviors of N-carbamyl-D-amino acid 
amidohydrolase”, Journal of the Chinese Institute of Chemical Engineers, 36 (2), 185-194 (March 2005) (NSC-93-2214-E-027-001) 
(SCI, impact factor: 0.333) [full text (PDF)]
42.
East Zhao, Hsuan-Liang Liu, Chi-Hung Tasi, Huai-Kuang Tsai, Chen-hsiung Chan, Cheng-Yan Kao*, “Cysteine separation profile on protein sequences 
infers disulfide connectivity”, Bioinformatics, 21 (8), 1415-1420 (April 15, 2005) (NSC-93-3112-B-002-022) 
(SCI, impact factor: 6.701) [abstract] [full text (PDF)]
43.
Hsuan-Liang Liu* and Jyh-Ping Hsu, “Recent developments in structural proteomics for protein structure determination”, Proteomics, 5 (8),
2056-2068 (May 2005) (NSC-93-2214-E-027-001) (SCI, impact factor: 5.766) (review paper)  [abstract] [full text (PDF)]
44.
Yann-Wen Lan, Hsuan-Liang Liu*, Yang-Chu Cheng, “Optimized physical parameters for high cell density cultivation of the indigenous Thiobacillus 
thiooxidans by response surface methodology”, Journal of the Chinese Institute of Chemical Engineers, 36 (3), 243-251 (May 2005)
(NSC 93-2214-E-027-005) (SCI, impact factor: 0.333) [full text (PDF)]
45.
Yuan-Cheng Su, Jin-Chung Lin, and Hsuan-Liang Liu*, “Homology model and molecular dynamics simulations of carp cystatin”,  Biotechnology Progress,
21 (4), 1315-1320 (August 2005) (NSC-93-2622-E-027-005-CC3) (SCI, impact factor: 1.821)
46.
Hsuan-Liang Liu* and Yun-Ru Chiou, “Optimal decolorization rate of Reactive Red 239 by UV/TiO2 photocatalytic process coupled with response surface 
methodology”, Chemical Engineering Journal, 112 (1-3), 173-179 (Sept. 1, 2005) (NSC-93-2622-E-027-005-CC3) (SCI, impact factor: 2.034)
47.
Chin-Wen Chen, Jin-Chung Lin, and Hsuan-Liang Liu*, Molecular dynamics simulations of the tetramerization domain of Shaker and Kv1.1 
potassium channels", Journal of the Chinese Institute of Chemical Engineers, 36 (6), 649-660 (Nov., 2005) (NSC-94-2622-E-027-007-CC3) 
(SCI, impact factor: 0.333)
48.
Chi-Hung Tsai, Bo-Juen Chen, Chen-Hsiung Chan, Hsuan-Liang Liu, and Cheng-Yan Kao*, “Improving Disulfide Connectivity Prediction 
with Sequential Distance between Oxidized Cysteines”, Bioinformatics, 21 (24), 4416-4419 (Dec. 15, 2005) (SCI, impact factor: 6.701)
49.
Chin-Wen Chen, Hsuan-Liang Liu*, Jin-Chung Lin, and Yih Ho, “Molecular modeling of the chelating of various metal ions to the His-tag motif: 
A molecular dynamics study”, Journal of Chinese Chemical Society, 52 (6), 1281-1290 (Dec., 2005) (NSC-94-2622-E-027-007-CC3) 
(SCI, impact factor: 0.534)
2006
50.
Jian-Hua Zhao and Hsuan-Liang Liu*, “The effects of various alcohols on the structural stability of melittin, TH-10Aox, 
and Tc1 by molecular dynamics simulations”, Chemical Physics Letters, 420 (1-3), 235-240 (March 10, 2006)
(NSC-94-2622-E-027-007-CC3) (SCI, impact factor: 2.526)
51.
Bor-Yann Chen*, Hsuan-Liang Liu, Yun-Wen Chen and Yang-Chu Cheng, Synergistic Interactions of Binary Metal Toxicity to IndigenousThiobacillus 
thiooxidans”, Journal of the Chinese Institute of Chemical Engineers, 37 (3), 217-225 (May 2006) (SCI, impact factor: 0.333)
52.
Hsuan-Liang Liu* and Yun-Ru Chiou, “Optimal decolorization rate of Reactive Red 239 by UV/ZnO photocatalytic process”, 
 Journal of the Chinese Institute of Chemical Engineers, 37 (3), 289-298 (May 2006) (SCI, impact factor: 0.333)
53.
Yuan-Chen Su and Hsuan-Liang Liu*, “The effects of salt and pH on the spermatozoa agglutinating activity of carp ovum cystatin 
by molecular dynamics simulations”, Journal ofChinese Chemical Society, 53 (3), 713-720 (June, 2006) (SCI, impact factor: 0.534)
54.
Jin-Chung Lin and Hsuan-Liang Liu*, “Protein conformational diseases: from mechanisms to drug designs”,
Current Drug Discovery Technologies, 3 (2), 145-153 (June 30, 2006) (NSC-94-2214-E-027-002) (Invited review)
56.
Hsu-Wei Fang*,Yi-Ching Ho, Charng-Bin Yang, Hsuan-Liang Liu, Fang-Yuan Ho, Yung-Chang Lu, Hon-Ming Ma, Chun-Hsiung Huang, 
“Preparation of UHMWPE particles and establishment of inverted macrophage cell model to investigate wear particles induced bioactivities”, 
Journal of Biochemical and Biophysical Methods, 68, 175-187 (Oct. 2006) (SCI, impact factor: 1.302)
57.
Hsuan-Liang Liu*, Yi-Ching Wu, Jian-Hua Zhao, Hsu-Wei Fang, and Yih Ho, “Structural analysis of human lysozyme using 
molecular dynamics simulations”, Journal of Biomolecular Structure and Dynamics, 24 (3), 229-238 (Dec., 2006) 
(NSC-95-2221-E-027-089) (SCI, impact factor: 1.407)
58.
Charng-Bin Yang, Hsu-Wei Fang*, Hsuan-Liang Liu, Chih-Hung Chang, Man-Ching Hsieh, Wei-Ming Lee, Huei-Ting Huang, 
“Frictional characteristics of the tribological unfolding albumin for polyethylene and cartilage”, Chemical Physics Letters,
431 (4-6), 380-384 (Dec. 1, 2006) (SCI, impact factor: 2.526)
59.
Hsu-Wei Fang*, Charng-Bin Yang, Chih-Hung Chang, Chun-Hsiung Huang, Hsuan-Liang Liu, Shiuh-Bin Fang, 
The potential role of phagocytic capacity in osteolytic process induced by polyethylene wear particles” 
Journal of International Medical Research, 34, 655-664 (Dec. 2006) (SCI, impact factor: 0.523)
2007
60.
Hsuan-Liang Liu*, “Recent advances in disulfide connectivity predictions”, Current Bioinformatics, 2 (1), 31-47 
(Jan. 2007) (NSC-95-2221-E-027-089) (Review paper)
62.
Hsuan-Liang Liu*, Yi-Ching Wu, Jian-Hua Zhao, Yi-Fan Liu, Chi-Hung Huang, Hsu-Wei Fang, and Yih Ho, “Insights into the 
conformational changes of several human lysozyme variants associated with hereditary systemic amyloidosis”,  
Biotechnology Progress, 23 (1), 246-254 (Feb. 02, 2007) (NSC 95-2214-E-027-001) (SCI, impact factor: 1.821)
63.
Hsuan-Liang Liu*, Fu-Chiang Yang, Chi-Hung Huang, Hsu-Wei Fang, Yung-Chu Cheng, “Sensitivity analysis of the semiempirical 
model for the growth of the indigenous Acidithiobacillus thiooxidans”,  Chemical Engineering Journal, 129 (1-3), 105-112
(May 1, 2007) (NSC-95-2622-E-027-010-CC3) (SCI, impact factor: 2.034)
64.
Chih-Hung Chang, Hsu-Wei Fang*, Huei-Ting Huang, Hsuan-Liang Liu, Wei-Ming Lee, Man-Ching Hsieh, Chiang-San Chen, 
“Tribological process induced conformational transformation of protein may change the friction of cartilage”, 
Materials Letters, 61, 3381-3384 (May 2006) (SCI, impact factor: 1.299)
65.
Hsu-Wei Fang*, Meng-Lin Shih, Jian-Hua Zhao, Huei-Ting Huang, Hsin-Yi Lin, Hsuan-Liang Liu, Chih-Hung Chang, 
Charng-Bin Yang, and Hwa-Chang Liu, “Association of polyethylene friction and thermal unfolding of interfacial albumin molecules”, 
Applied Surface Science, 253, 6896-6904 (May 2007) (SCI, impact factor:: 1.263)
66.
Yuan-Min Lin, Hsuan-Liang Liu*, Jian-Hua Zhao, Chi-Hung Huang, Hsu-Wei Fang, Yih Ho, and Wen-Yih Chen, 
“Molecular Dynamics Simulations to Investigate the Domain Swapping Mechanism of Human Cystatin C”, 
Biotechnology Progress, 23 (3), 577-584 (June 2007) (NSC 95-2221-E-027-089) (SCI, impact factor: 1.821)
67.
Chi-Hung Tsai, Bo-Juen Chen, Chen-Hsiung Chan, Cheng-Yan Kao, Hsuan-Liang Liu*, and Jyh-Ping Hsu*, “Bioinformatics Approaches 
for Disulfide Connectivity Prediction”, Current Protein & Peptide Science, 8 (3), 243-260 (June 2007) 
(NSC-94-2214-E-027-002) (invited review) (SCI, impact factor: 0.77)
68.
Jian-Hua Zhao, Hsuan-Liang Liu*, Hsin-Yi Lin, Chih-Hung Huang, Hsu-Wei Fang, and Shau-Wei Tsai, “Semiempirical molecular 
orbital studies of the acylation step in the lipase-catalyzed ester hydrolysis”, Journal of the Chinese Chemical Society, 
54 (4), 835-842 (Aug. 2007) (NSC 94-2622-E-027-007-CC3) (SCI, impact factor: 0.534) 

69.

Hsuan-Liang Liu*, Yuan-Min Lin, Jian-Hua Zhao, Man-Ching Hsieh, Hsin-Yi Lin, Chi-Hung Huang, Hsu-Wei Fang,

Yih Ho, and Wen-Yih Chen, “Molecular Dynamics Simulations of Human Cystatin C and Its L68Q Varient to Investigate

the Domain Swapping Mechanism”, Journal of Biomolecular Structure & Dynamics, 25 (2), 135-144

(Oct. 2007) (SCI, impact factor: 1.407)

70.

Hsuan-Liang Liu*, Ching-Tao Yang, Jian-Hua Zhao, Chi-Hung Huang, Hsin-Yi Lin, Hsu-Wei Fang, Yih Ho, 
Wei-Bor Tsai, “Molecular Dynamics Simulations to Investigate the Effects of Zinc Ions on the Structural Stability 
of the c-Cbl RING Domain”, Biotechnology Progress, 23 (5), 1231-1238 (Oct. 2007) (SCI, impact factor: 1.821)

71.

Jian-Hua Zhao, Hsuan-Liang Liu*, Hsin-Yi Lin, Chi-Hung Huang, Hsu-Wei Fang, Shiao-Shing Chen, Yih Ho, Wei-Bor Tsai, 
Wen-Yih Chen, “Chemical chaperone and inhibitor discovery: potential treatments for protein conformational diseases”, 
Perspectives in Medicinal Chemistry, 1, 39-48 (Dec. 10, 2007)
2008

72.

Hsu-Wei Fang*, Hsien-Chieh Wang, Teh-Hua Tsai, Wei-Bor Tsai, Shao-Yi Hou, Hsuan-Liang Liu, Wun-Hsin Lee, 
Yung-Chang Lu, Chun-Hsiung Huang, “An accelerated wear testing with microfabricated surface to evaluate the 
lubrication ability of biomolecules on polyethylene”,  Journal of Applied Polymer Science, 108, 2428-2437
(Feb. 2008) (SCI, impact factor: 1.306)
73.
Hsuan-Liang Liu*, Fu-Chiang Yang, Hsin-Yi Lin, Chi-Hung Huang, Hsu-Wei Fang,  Wei-Bor Tsai, Yung-Chu Cheng, 
Artificial neural network to predict the growth of the indigenous Acidthiobacillus thiooxidans ”, Chemical Engineering Journal, 
137 (2), 231-237 (April 2008) (NSC 95-2622-E-027-010-CC3) (SCI, impact factor: 2.034)
Accepted

74.

Yi-Ching Ho, Shao-Yi Hou, Tzan Fang, Hsuan-Liang Liu, Hsu-Wei Fang*, “Effect of electrostatic field on proliferation 
and cytokine secretion of macrophage cells”, Accepted for publication in Biomedical Engineering-Applications, 
Basis and Communications (Accepted date: Dec. 19, 2007) (EI)

75.

Jung-Yen Yang, Yen-Chung Ting, Juin-Yih Lai, Hsuan-Liang Liu, Hsu-Wei Fang, Wei-Bor Tsai*, 
“Quantitative analysis of osteoblast-like cells (MG63) morphology on nanogrooved substrata with various groove and ridge 
dimensions”, Accepted for publication in the Journal of Biomedical Materials Research: Part A 
(Accepted date: Jan. 14, 2008) (SCI, impact factor: 2.497)

81.

Jian-Hua Zhao, Ching-Tao Yang, Josephine W. Wu, Wei-Bor Tsai, Hsin-Yi Lin, Hsu-Wei Fang, Yih Ho, 
and Hsuan-Liang Liu*, “RING Domains with E3 Ligase Functions Reveal Distinct Structural Features: 
A Molecular Dynamics Simulation Study”, Accepted for publication in the Journal of Biomolecular Structure & Dynamics
(Accepetd date: March 28, 2008) (SCI, impact factor: 1.407)
In press

76.

Jian-Hua Zhao and Hsuan-Liang Liu*, “Protein structure determination”, in Randeep Rakwal (ed.), 
Plant Proteomics: Technologies, Strategies, and Applications, John Wiley & Sons, Inc., In press (Submitted date: Nov. 13, 2006)
 
In revision

77.

Hsuan-Liang Liu*, Yi-Fan Liu, Jian-Hua Zhao, Hsin-Yi Lin, Hsu-Wei Fang, Yih Ho, 
Wei-Bor Tsai, and Wen-Yih Chen, “Molecular Dynamics Simulations to Investigate the Aggregation Behaviors of 
the Ab(17-42) Oligomers”, Journal of Biomolecular Structure & Dynamics, In revision (Submitted date: Aug. 10, 2007) 
(SCI, impact factor: 1.821)

78.

Hsuan-Liang Liu*, Jung-Tang Huang, Po-Sheng Fang, Yi-Fan Liu, Ming-Kwang Hsu, Chiao-Ling Hsu, Jian-Sheng Liao, 
Wen-Hui Hsieh, Shao-Yi Hou, Chih-Hung Huang, Hsin-Yi Lin, Hsu-Wei Fang, and Wei-Bor Tsai, Recent Patents for Nucleic 
Acid Sequencing and Its Applications”, Recent Patents in Biotechnology, In revision (Submitted date: June 30, 2007)
Submitted

79.

Charng-Bin Yang, Hsu-Wei Fang*, Yu-Chih Su, and Hsuan-Liang Liu,An accelerated wear testing with microfabricated 
surface textures to investigate the friction induced conformational change of protein and wear of polyethylene”, 
Submitted to Materials Letters for publication (Submitted date: May 1, 2007) (SCI, impact factor: 1.299)

80.

Steven S.-S. Wang, Hsuan-Shen Chao, Hsuan-Liang Liu, and Hwai-Shen Liu*, “Stability of Hen Egg-White Lysozymes 
during Denaturation is Enhanced via Pretreatment in Supercritical Carbon Dioxide”, Submitted to the 
Journal of Supercritical Fluids for publication (Submitted date: Sept. 22, 2007) (SCI, impact factor: 2.037)

82.

Po-Sheng Fang, Jian-Hua Zhao, Pavadai Elumalai, Wei-Bor Tsai, Hsin-Yi Lin, Hsu-Wei Fang, Yih Ho, 
and Hsuan-Liang Liu*, “Molecular Dynamics Simulations to Investigate the Relationship between the Structural Stability 
and Amyloidogenesis of the Wild-type and N-terminal Hexapeptide Deletion DN6 b2-microglobulin”, Submitted to 
Biotechnology Progress for publication (Submitted date: March 6, 2008) (SCI, impact factor: 2.102)

 

Conference papers

1999

1.

Hsuan-Liang Liu and Peter J. Reilly, “Mutations to alter Aspergillus awamori glucoamylase selectivity”, The Fourth Conference on Biochemical Engineering,

pp. 123-126 (June 27-28, 1999, Cha-Yi, Taiwan)

2.

Hsuan-Liang Liu and Peter J. Reilly, “Mutational analysis of Aspergillus awamori glucoamylase selectivity to increase glucose yield”, 化學感測器技術交流

研討會, pp. B-6, (June 25, 1999, Hsin-Chu, Taiwan)

3.

Hsuan-Liang Liu and Peter J. Reilly, “Mutations to improve substrate selectivity of glucoamylase from Aspergillus awamori”, 99’石延平教授追思紀念

學術研討會, pp.33-38 (Nov. 13, 1999, Taipei, Taiwan)

4.

James I. Chang, Hsuan-Liang Liu, C. H. Chen and George S.Y. Liu, “Waste minimization at a nitrocellulose manufacturing facility”, International conference

on cleaner production and sustainable development ’99, pp.113-122 (Dec. 13-17, 1999, Taipei, Taiwan)

2000

5.

劉宣良, 李紹銘, “利用分子模擬方法探討葡萄糖轉化酵素之linker domain結構的研究”, The Fifth Conference on Biochemical Engineering,

pp.449-452 (June 27-28, 2000, Tainan, Taiwan)

6.

陳博彥, 劉宣良, 吳東峻, 鄭陽助, “本土性嗜酸性硫氧化硫化桿菌之優勢馴養評估”, The Fifth Conference on Biochemical Engineering,

pp.541-544 (June 27-28, 2000, Tainan, Taiwan)

7.

劉宣良, 陳博彥, 吳東峻, 王國明, 陳彥承, 黃淑苓, 鄭陽助, “瀝取土壤鎘污染之硫氧化菌之氧化特性評估”, The Fifth Conference on

Biochemical Engineering, pp. 635-638 (June 27-28, 2000, Tainan, Taiwan)

8.

劉宣良, 陳博彥, 黃春福, 曾宏源, 董進富, 鄭陽助, “利用Aspergillus terrus M8進行味精發酵廢液生產衣康之可行性研究”,

The Fifth Conference on Biochemical Engineering, pp. 639-642 (June 27-28, 2000, Tainan, Taiwan)

2001

9.

劉宣良, 陳博彥, 吳東峻, 陳韻文, 鄭陽助, “以硫氧化硫化桿菌進行生物溶提之可行性研究” The Sixth Conference on Biochemical Engineering,

pp. 59-62 (June 29-30, 2001, Chung-Li, Taiwan)

10.

鄭陽助, 陳博彥, 劉宣良, 陳韻文, 吳東峻, “硫氧化硫化桿菌對重金屬毒性容忍度之研究”, The Sixth Conference on Biochemical Engineering,

pp. 285-288 (June 29-30, 2001, Chung-Li, Taiwan)

11.

劉宣良, 李紹銘, “利用電腦分子模擬探討多醣集結對來自Aspergillus awamori菌種的glucoamylaselinker domain結構穩定 性影響的探討”,

The Sixth Conference on Biochemical Engineering, pp. 435-438 (June 29-30, 2001, Chung-Li, Taiwan)

12.

劉宣良, 王文志, 李紹銘, “對來自Aspergillus菌種的glucoamylasecatalytic domain受熱導致a-helices結構瓦解動力機制探討,

The Sixth Conference on Biochemical Engineering, pp. 513-516 (June 29-30, 2001, Chung-Li, Taiwan)

2002

13.

劉宣良, 王文志, 胡佳筠, “以分子動態模擬研究glucoamylasecatalytic domain二級結構瓦解的動力機制, The Seventh Conference on

Biochemical Engineering, pp. 267-272 (June 28-29, 2002, Taipei, Taiwan)

14.

劉宣良, 許家銘, 黃明儀, “以分子模擬決定金屬離子對人體酒精去氫酵素b2b2之影響, The Seventh Conference on Biochemical Engineering,

pp. 273-276 (June 28-29, 2002, Taipei, Taiwan) [poster]

15.

劉宣良, 林原銘, 蘇彥綺, “以分子動態模擬探討b-hairpin在不同溶液狀態下的結構”, The Seventh Conference on Biochemical Engineering,

pp. 277-280 (June 28-29, 2002, Taipei, Taiwan) [poster]

16.

劉宣良, 鍾榮哲, 鄭富元, “以分子動態模擬探討MelittinPolyLeuPOPC在水分子影響下之作用”, The Seventh Conference on

Biochemical Engineering, pp. 281-284 (June 28-29, 2002, Taipei, Taiwan) [poster]

17.

鄭陽助, 陳博彥, 劉宣良, 陳韻文, 藍彥文, 張志偉, “本土性硫氧化硫化桿菌對重金屬劑量效應之研究, The Seventh Conference on

Biochemical Engineering, pp. 285-289 (June 28-29, 2002, Taipei, Taiwan)

18.

劉宣良, 陳博彥, 張皙聖, 邱啟偉, 鄭光博, 鄭陽助, “本土性硫氧化硫化桿菌之生長代謝物對重金屬瀝取效應之研究”,

The Seventh Conference on Biochemical Engineering, pp. 291-294 (June 28-29, 2002, Taipei, Taiwan) [poster]

19.

鄭陽助, 劉宣良, 陳博彥, 林中琳, “取代性硫基質於硫氧化硫化桿菌培養之可行性評估”, The SeventhConference on Biochemical Engineering,

pp. 1171-1174 (June 28-29, 2002, Taipei, Taiwan) (論文競賽特優獎) [poster]

20.

鄭陽助, 劉宣良, 陳博彥, 陳韻文, “本土性硫氧化硫化桿菌之硫氧化代謝機制研究”, The Seventh Conference on Biochemical Engineering,

pp. 1175-1180 (June 28-29, 2002, Taipei, Taiwan) [poster]

21.
Hsuan-Liang Liu and Wen-Chi Wang, “Molecular Dynamics Simulations of the Unfolding Mechanism of the Catalytic Domain from Aspergillus awamori 
var. X100 Glucoamylase”, YABEC 2002 (Nov. 10-11, 2002, Taipei, Taiwan)
2003
22.
Hsuan-Liang Liu and Chia-Ming Hsu, “The Effect of Metal Ions on the Binding of Ethanol to Human Alcohol Dehydrogenase β2β2”, 
The eighth Conference on Biochemical Engineering (June 27-28, 2003, Kaohsiung, Taiwan) 
23.
Hsuan-Liang Liu, Chia-Ming Hsu, and Chiao-Kai Hwang, “The effects of solvent and temperature on the structural integrity of monomeric  melittin by 
molecular dynamics simulations”, The eighth Conference on Biochemical Engineering (June 27-28, 2003, Kaohsiung, Taiwan) [poster]
24.
Hsuan-Liang Liu, Bor-Yann Chen, Yann-Wen Lan, and Yang-Chu Cheng, “SEM and AFM images of pyrite surfaces after bioleaching by the indigenous 
Thiobacillus thiooxidans”, The eighth Conference on Biochemical Engineering (June 27-28, 2003, Kaohsiung, Taiwan)
25.
Hsuan-Liang Liu, Bor-Yann Chen, Yann-Wen Lan, and Yang-Chu Cheng, “Biosorption of Zn(II) and Cu(II) by the indigenous Thobacillus thiooxidans”, 
The eighth Conference on Biochemical Engineering (June 27-28, 2003, Kaohsiung, Taiwan) [poster]
26.
Hsuan-Liang Liu, Jin-Chung Lin, and Jen-Hua Chiao, “Structural models of the pore loop domain of six eukaryotic voltage-gated potassium channels 
Kv1.1–Kv1.6”, The eighth Conference on Biochemical Engineering (June 27-28, 2003, Kaohsiung, Taiwan) [poster]
27.
劉宣良, 謝偉強, 葉文秀, “二氧化碳在常壓與超臨界流體對Hen Egg White Lysozyme結構穩定性的影響”, The eighth Conference on 
Biochemical Engineering (June 27-28, 2003, Kaohsiung, Taiwan) [poster]
28.
Yih Ho, Hsuan-Liang Liu, Ming-Rong Hsieh, Li Hsueh Tsai, and Kuang-Yang Hsu, “Pharmacokinetic study of cinnamicacid and its metabolite in rabbits”, 
92年度中國藥學會年會暨藥學學術研討會 (Dec. 7, 2003, Taipei, Taiwan)
2004
29.
Bor-Yann Chen, Jo-Shu Chang, Hsuan-Liang Liu, and Yang-Chu Cheng, “Metal toxicity assessment upon Thiobacillus thiooxidans BC1 and 
Pseudomonas aeruginosa PU21 for metal bioremediation” The fourth international conference on Remediation of Chlorinated and Recalcitrant Compounds
(May 24-27, 2004, Monterey, CA, USA)

30.

Hsuan-Liang Liu, Jin-Chung Lin, “Molecular docking of the scorpion toxin Tc1 to the structural model of the voltage-gated potassium channel Kv1.1 
from human Homo sapiens”, The Ninth Conference on Biochemical Engineering (June 25-26, 2004, Chang-Hua, Taiwan)
31.
Hsuan-Liang Liu, Wei-Chan Hsieh, “Molecular dynamics simulations to investigate the thermal unfolding behaviors of N-carbamyl-D-amino acid 
amidohydrolase”, The Ninth Conference on Biochemical Engineering (June 25-26, 2004, Chang-Hua, Taiwan)(壁報論文競賽優等獎)
[poster] [full text (PDF)]

32.

Hsuan-Liang Liu and Chin-Wen Chen, “Homology models of the tetramerization domain of six eukaryotic voltage-gated potassium channels 
Kv1.1-Kv1.6”, The Ninth Conference on Biochemical Engineering (June 25-26, 2004, Chang-Hua, Taiwan) [poster] [full text (PDF)]

33.

Hsuan-Liang Liu and Yuan-Cheng Su, “Homology model and molecular dynamics simulations of carp cystatin”, The Ninth Conference on 
Biochemical Engineering (June 25-26, 2004, Chang-Hua, Taiwan) [poster] [full text (PDF)]

34.

Hsuan-Liang Liu, Chao-Kai Huang, Jin-Chung Lin, “The stabilizing effects of O-glycosylation on the secondary structural integrity of the designed 
a-loop-a motif”, The Ninth Conference on Biochemical Engineering (June 25-26, 2004, Chang-Hua, Taiwan) [poster] [full text (PDF)]

35.

Yang-Chu Cheng, Hsuan-Liang Liu, Bor-Yann Chen, Yann-Wen Lan, “Optimal high cell density in the cultivation of the indigenous Acidithiobacillus 
thiooxidans for optimizing physical parameters by using response surface methodology”, The Ninth Conference on Biochemical Engineering 
(June 25-26, 2004, Chang-Hua, Taiwan)(論文競賽口頭報告優等獎)
36.
鄭陽助, 陳博彥, 劉宣良, 林劍壕, “高密度本土性嗜酸性硫氧化硫化桿菌最適化生物促進生長策略”, 第九屆生化工程研討會 
(June 25-26, 2004, Chang-Hua, Taiwan)
2005

37.

Jin-Chung Lin, Xiang-Jun Zheng, and Hsuan-Liang Liu*, "Molecular docking of the scorpion toxin Tc1 to the structural model of the voltage-gated 
potassium channel Kv1.1 from human Homo sapiens",  The Tenth Conference on Biochemical Engineering (June 24-25, 2005, Taipei, Taiwan)

38.

Chin-Wen Chen, Jin-Chung Lin, and Hsuan-Liang Liu*, "Homology models and molecular dynamics simulations of the tetramerization domain of

six eukaryotic voltage-gated potassium channels Kv1.1-Kv1.6", The Tenth Conference on Biochemical Engineering (June 24-25, 2005, Taipei, Taiwan)

39.

Yuan-Chen Su, Jin-Chung Lin, and Hsuan-Liang Liu*, "The effects of salt and pH on the structural integrity of carp ovum cystatin by molecular

dynamics simulations", The Tenth Conference on Biochemical Engineering (June 24-25, 2005, Taipei, Taiwan)

40.

Jian-Hua Zhao, Jin-Chung Lin, Pei-Ling Cai, and Hsuan-Liang Liu*, "The effects of various alcohols on the structural stability of melittin, TH-10Aox,

and Tc1 by molecular dynamics simulations", The Tenth Conference on Biochemical Engineering (June 24-25, 2005, Taipei, Taiwan)

41.

Fu-Chiang Yang, Hsuan-Liang Liu*, Yung-Chu Cheng, "The Modeling and Sensitivity Analysis of High Cell Density Cultivation of the Indigenous

Thiobacillus Thiooxidans in a Batch Reactor", The Tenth Conference on Biochemical Engineering (June 24-25, 2005, Taipei, Taiwan)

42.

B.-Y. Chen*, J.-S. Chang, H.-L. Liu, Y.-C. Cheng, Y.-H. Lee, T.-F. Kuo, W.-M. Chen, "Case Study on Threshold Operation Strategy for
Environmental Biotechnology", The Tenth Conference on Biochemical Engineering (June 24-25, 2005, Taipei, Taiwan)

43.

林原銘, 林進中, 劉一帆, 劉宣良*, “由蛋白質資料庫中探討雙硫鍵所在位置之二級結構對蛋白質熱穩定性的影響”, 
中國化學工程學會94年年會 (Nov. 19-20, 苗栗)
2006

44.

Jian-Hua Zhao, Hsuan-Liang Liu*, Yung-Chu Cheng, " Semiempirical Molecular Orbital Studies of the Catalytic Mechanism 
for Ester Hydrolysis by Serine Hydrolases", The Eleventh Conference on Biochemical Engineering (June 24-25, 2006, HsinChu, Taiwan)

45.

Yi-Ching Wu, Jian-Hua Zhao, Hsuan-Liang Liu*, “Molecular Dynamics Simulations to Investigate the Effects of Ethanol

and Temperature on the Structural Integrity of Human Lysozyme, The Eleventh Conference on Biochemical Engineering

(June 24-25, 2006, HsinChu, Taiwan)

46.

Yuan-Min Lin, Jian-Hua Zhao, Hsuan-Liang Liu*, “Insights into the Domain Swapping Pathway of Human Cystatin C by 
Thermal Unfolding Simulations”, The Eleventh Conference on Biochemical Engineering (June 24-25, 2006, HsinChu, Taiwan)

47.

Fu-Chiang Yang, Hsuan-Liang Liu*, Yung-Chu Cheng, “Sensitivity Analysis of the Semi-empirical Model for the Growth 
of Thiobacillus thiooxidans”, The Eleventh Conference on Biochemical Engineering (June 24-25, 2006, HsinChu, Taiwan)

48.

Yi-Fan Liu, Hsuan-Liang Liu*, “The Effects of Various Solvents on the Structural Propensities of Ab1-40 by Molecular 
Dynamics Simulations”,  The Eleventh Conference on Biochemical Engineering (June 24-25, 2006, HsinChu, Taiwan)

49.

Ching-Tao Yang, Jian-Hua Zhao, Hsuan-Liang Liu*, “The Effects of Zinc Ions on the Structural Integrity of Cbl Domain: 
Insight from Thermal Denaturation Simulations”, The Eleventh Conference on Biochemical Engineering 
(June 24-25, 2006, HsinChu, Taiwan)
2007

50.

 Yi-Fan Liu, Jian-Hua Zhao, Hsuan-Liang Liu*, “Different aggregative behaviors of two hydrophobic segments of Ab(17-42): 
A molecular dynamics study”, The Twelfth Conference on Biochemical Engineering (June 29-30, 2007, Taoyuan, Taiwan)

51.

 Ching-Tao Yang, Jian-Hua Zhao, Hsuan-Liang Liu*, “Molecular dynamics simulations to investigate the effects of 
zinc ions on the structural integrity of the c-Cbl RING domain”, The Twelfth Conference on Biochemical Engineering 
(June 29-30, 2007, Taoyuan, Taiwan)

52.

Po-Sheng Fang, Jian-Hua Zhao, Hsuan-Liang Liu*, “Molecular dynamics simulations to investigate the structural stability of 
the native and N-terminal hexapeptide deletion DN6 b2-microglobulin, The Twelfth Conference on Biochemical Engineering 
(June 29-30, 2007, Taoyuan, Taiwan)

53.

Jian-Hua Zhao and Hsuan-Laing Liu*, "Semiempirical molecular orbital studies: the mechanism of the lipase-catalyzed ester 
hydrolysis in acylation step", European Congress of Chemical Engineering - 6 (Copenhagen, 16-20 September 2007)

54.

 Po-Sheng Fang, Hsuan-Liang Liu*, “Molecular dynamics simulations to investigate the structural stability of wild-type and N-terminal 
hexapeptide deletion DN6 b2-microglobulin, 2007台灣化學工程學會第54屆年會 (Nov. 23-24, 2007, Taoyuan, Taiwan)

55.

 Jian-Hua Zhao, Yu-Jie Wang, and Hsuan-Laing Liu*, "Semiempirical molecular orbital studies activation of Ser70 in the acylation 
mechanism of a class A b-lactamase with penicillin",  2007台灣化學工程學會第54屆年會 (Nov. 23-24, 2007, Taoyuan, Taiwan)
Patent
1.

Martin Allen, Hsiu-Mei Chen, Pedro Coutinho, Tsuei-Yun Fang, Clark Ford, Richard Honzatko, Yuxing Li, Hsuan-Liang Liu, “Protein Engineering

of Glucoamylase to Increase pH Optimum, Substrate Specificity and Thermostability”, patent number: 6,537,792, USA, March 25, 2003.

 

Updated : March 28, 2008

 

 

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